Atherosclerosis is a disease in which plaque builds up inside arteries. Arteries are blood vessels that carry oxygen-rich blood to heart and other parts of your body.
Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows arteries. This limits the flow of oxygen-rich blood to organs and other parts of your body.
Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death.
Atherosclerosis usually doesn't cause signs and symptoms until it severely narrows or totally blocks an artery. Many people don't know they have the disease until they have a medical emergency, such as heart attack or stroke.
Some people may have signs and symptoms of the disease. Signs and symptoms will depend on which arteries are affected.
The coronary arteries supply oxygen-rich blood to heart. If plaque narrows or blocks these arteries (a disease called coronary heart disease, or CHD), it may lead to angina. Angina is chest pain or discomfort that occurs when heart muscle doesn't get enough oxygen-rich blood.
Angina may feel like pressure or squeezing in chest. Pain may also be felt in shoulders, arms, neck, jaw, or back. Angina pain may even feel like indigestion. The pain tends to get worse with activity and go away with rest. Emotional stress also can trigger the pain.
Other symptoms of CHD are shortness of breath and arrhythmias Arrhythmias are problems with the rate or rhythm of the heartbeat.
Plaque also can form in the heart's smallest arteries. This disease is called coronary microvascular disease (MVD). Symptoms of coronary MVD include angina, shortness of breath, sleep problems, fatigue (tiredness), and lack of energy.
The carotid arteries supply oxygen-rich blood to brain. If plaque narrows or blocks these arteries (a disease called carotid artery disease), one may have symptoms of stroke. These symptoms may include:
Plaque also can build up in the major arteries that supply oxygen-rich blood to the legs, arms, and pelvis (a disease called peripheral artery disease).
If these major arteries are narrowed or blocked, you may have numbness, pain, and sometimes dangerous infections.
The renal arteries supply oxygen-rich blood to kidneys. If plaque builds up in these arteries, one may develop chronic kidney disease. Over time, chronic kidney disease causes a slow loss of kidney function.
Early kidney disease often has no signs or symptoms. As the disease gets worse, it can cause tiredness, changes in how you urinate (more often or less often), loss of appetite, nausea (feeling sick to the stomach), swelling in the hands or feet, itchiness or numbness and trouble concentrating.
The exact cause of atherosclerosis isn't known. However, studies show that atherosclerosis is a slow, complex disease that may start in childhood. It develops faster as you age.
Atherosclerosis may start when certain factors damage the inner layers of the arteries. These factors include:
The exact cause of atherosclerosis is not clear but certain traits, conditions, or habits may raise risk for the disease. These conditions are known as risk factors. The more risk factors you have, the more likely it is that you'll develop atherosclerosis.
Major Risk Factors
Physical examination may show weak or absent pulse (e.g. in leg or foot). A weak or absent pulse can be a sign of blocked artery.
One or more tests may be required to diagnose atherosclerosis. Extent of disease so determined by tests, helps in planning the treatment.
Blood tests check the levels of certain fats, cholesterol, sugar, and proteins in blood. Abnormal levels may be a sign that you're at risk for atherosclerosis.
An ECG can show signs of heart damage caused by CHD. The test also can show signs of a previous or current heart attack.
Chest x- Ray
A chest x- ray takes pictures of the organs and structures inside your chest, such as your heart, lungs, and blood vessels. A chest x ray can reveal signs of heart failure.
This test compares the blood pressure in your ankle with the blood pressure in your arm to see how well your blood is flowing. This test can help diagnose P.A.D (Peripheral Arterial Disease).
Other tests are being studied to see whether they can give a better view of plaque build up in the arteries. Examples of these tests include magnetic resonance imaging (MRI) and positron emission tomography (PET).
Sometimes lifestyle changes alone aren’t enough to control cholesterol levels. For example, one may also need statin medications to control or lower cholesterol. By lowering blood cholesterol level, one can decrease chances of having a heart attack or stroke.
Medical Procedures and Surgery
Patients with severe atherosclerosis may require a medical or surgical procedure.
Taking action to control risk factors can help prevent or delay atherosclerosis and related diseases. Risk for atherosclerosis increases with the number of risk factors you have.
Doctor may recommend medical advice along with heart-healthy lifestyle changes if you have atherosclerosis. Heart-healthy lifestyle changes include heart-healthy eating, maintaining a healthy weight, managing stress, physical activity and quitting smoking.
Doctor may recommend heart-healthy eating, which includes:
Maintaining a Healthy Weight
Maintaining a healthy weight is important for overall health and can lower risk for coronary heart disease. Knowing body mass index (BMI) helps in finding out a healthy weight in relation to height and give an estimate of total body fat.
A general goal is to aim for a BMI of less than 25. Doctor or health care provider can help set an appropriate BMI goal.
Learning how to manage stress, relax, and cope with problems can improve emotional and physical health. Consider healthy stress-reducing activities, such as:
Regular physical activity can lower many atherosclerosis risk factors, including LDL or “bad” cholesterol, high blood pressure, and excess weight. Physical activity also can lower risk for diabetes and raise HDL or “good” cholesterol, which helps prevent atherosclerosis.
If you smoke or use tobacco, quit. Smoking can damage and tighten blood vessels and raise risk for atherosclerosis. Take advice of doctor about programs and products that help in quitting. Also, try to avoid passive smoking. If you have trouble quitting smoking on your own, consider joining a support group. Many hospitals, workplaces, and community groups offer classes to help people quit smoking.